• 代表性成果(通讯&第一作者文章)

    • Xu T (corresponding author), Wu J, Chen Z, Zhao Li Z. Whole-Brain Map of Top-down afferent Inputs to Nucleus Accumbens of the Mouse. bioRxiv. 2022 Feb 02.478577. doi: https://doi.org/10.1101/2022.02.02.478577  link 

    • Liu Y, Wang S, Gong X, Wang Y and Xu T. Inhaled B7 alleviates bleomycin-induced pulmonary fibrosis in mice. Bioorganic & Medicinal Chemistry. 2021 Nov 15. Volume 50, 116482. link 

    • Zhang H, Wang X, Guo W, Li A, Chen R, Huang F, Liu X, Chen Y, Li N, Liu X, Xu T (co-corresponding author), Xue Z, Zeng S. Cross-Streams Through the Ventral Posteromedial Thalamic Nucleus to Convey Vibrissal Information. Frontiers in Neuroanatomy. 2021 Oct 28;15:724861. doi: 10.3389/fnana.2021.724861. eCollection 2021. link 

    • Chen Z, Xu T. rAAV2-retro enables extensive and efficient transduction of lower motor neurons following intramuscular injection. Mol Ther Methods Clin Dev. 2019 Nov 21; 17:21-33.  doi: 10.1016/j.omtm.2019.11.006. eCollection 2020 Jun 12. link 

    • Li Z, Chen Z, Fan G, Li A, Yuan J, Xu T. Cell-Type-Specific Afferent Innervation of the Nucleus Accumbens Core and Shell. Frontiers in Neuroanatomy. 2018 Dct 16; 12:84. doi: 10.3389/fnana.2018.00084. eCollection 2018. link

    • Zhao Y, Zhang C, Yu T, Luo Q, Xu T (co-corresponding author), Zhu D. Skull optical clearing window for in vivo imaging of the mouse cortex at synaptic resolution. Light: Science & Applications. 2018 Feb 23;7, 17153; doi:10.1038/lsa.2017.153. link

    • Wang S, Zhu J, Xu T. 17β-estradiol (E2) promotes growth and stability of new dendritic spines via estrogen receptor β pathway in the intact mouse cortex. Brain Research Bulletin. 2017 Dec 27; 137:241-248. link

    • Cui Y, Lv G, Jin S, Peng J, Yuan J, He X, Gong H, Xu, F, Xu T (co-corresponding author), Li H. A Central Amygdala-Substantia Innominata Neural Circuitry Encodes Aversive Reinforcement Signals. Cell Reports. 2017 Nov 14;21(7):1770-1782. link

    • Xu T, Wang SF, Lalchandani RR, Ding JB. Motor Learning in Animal Models of Parkinson’s disease: Aberrant Synaptic Plasticity in the Motor Cortex. Movement Disorders. 2017 Mar 25; 32(4):487-497. (Review) link

    • Shu Y, Xu T. Chronic Social Defeat Stress Modulates Dendritic Spines Structural Plasticity in Adult Mouse Frontal Association Cortex. Neural Plasticity. 2017 Jan 18:6207873. link

    • Guo L, Xiong H, Kim JI, Wu YW, Lalchandani RR, Cui Y, Shu Y, Xu T (co-corresponding author), Ding JB. Dynamic rewiring of neural circuits in the motor cortex in mouse models of Parkinson’s disease. Nature Neuroscience. 2015 Sep; 18(9):1299-309. link (Previewed by: Paolo Calabresi & Massimiliano Di Filippo, Nature Neuroscience. 2015 Sep; 8(9):1196-8)

    • Xu T, Yu X, Perlik AJ, Tobin WF, Zweig JA, Tennant K, Jones T, Zuo Y. Rapid formation and selective stabilization of synapses for enduring memories. Nature. 2009 Dec 17; 462, 915-920. link (Previewed by: Noam E. Ziv and Ehud Ahissar, Nature. 2009 Dec 17;462(7275):859-61)

    • Xu T, Nie L, Zhang Y, Mo J, Feng W, Wei D, Petrov E, Calisto LE, Kachar B, Beisel KW, Vazquez AE, Yamoah EN. Roles of alternative splicing in the functional properties of inner ear-specific KCNQ4 channels. Journal of Biological Chemistry. 2007 Aug; 282(33), 23899-23909. link


  • 参与成果

    • Xiong B, Li A, Lou Y, Chen S, Long B, Peng J, Yang Z, Xu T, Yang X, Li X, Jiang T, Luo Q, Gong H. Precise cerebral vascular atlas in stereotaxic coordinates of whole mouse brain. Frontiers in Neuroanatomy. 2017 Dec 19; 11:128. doi: 10.3389/fnana.2017.00128. eCollection 2017.

    • Gong H, Xu D, Yuan J, Li X, Guo C, Peng J, Li Y, Schwarz LA, Li A, Hu B, Xiong B, Sun Q, Zhang Y, Liu J, Zhong Q, Xu T, Zeng S, Luo Q. High-throughput dual-colour precision imaging for brain-wide connectome with cytoarchitectonic landmarks at the cellular level. Nature Communication. 2016 Jul 4; 7:12142.

    • Xiong H, Zhou Z, Zhu M, Lv X, Li A, Li S, Li L, Yang T, Wang S, Yang Z, Xu T, Luo Q, Gong H, Zeng S. Chemical reactivation of quenched fluorescent protein molecules enables resin-embedded fluorescence microimaging. Nature Communications. 2014 Jun 2; 5:3992.

    • Yu X, Wang G, Gilmore A, Yee AX, Li X, Xu T, Smith SJ, Chen L, Zuo Y. Accelerated experience-dependent pruning of cortical synapses in ephrin-A2 knockout mice. Neuron. 2013 Oct 2; 80(1):64-71.

    • Gong H, Zeng S, Yan C, Lv X, Yang Z, Xu T, Feng Z, Ding W, Qi X, Li A, Wu J, Luo Q. Continuously tracing brain-wide long-distance axonal projections in mice at a one-micron voxel resolution. Neuroimage. 2013 Jul 1;74:87-98.

    • Wang J, Zhang Y, Xu T, Luo Q, Zhu D. An innovative transparent cranial window based on skull optical clearing. Laser Physics Letters. 2012 Mar; 9, 469-473.